WASHINGTON - Texas Attorney General Ken Paxton ousted four-term U.S. Senator John Cornyn on Tuesday, riding President Donald Trump's endorsement to a runoff victory for the Republican Senate nomination, U.S. media projected.

The race was called shortly after polls closed in Texas' westernmost counties, which are in a separate time zone from most of the state.

"Without a shadow of a doubt, I will be the Democrats' No. 1 target in November," Paxton said in his victory speech. "Texas will be the radical left's No. 1 priority, but ... we're not going to let them take it."

Paxton's win will force Cornyn into retirement early next year - and the Republican political establishment in Washington into embracing a candidate it has long opposed.

Cornyn, 74, was backed by Republican leadership in the fight of his political life against Paxton, a 63-year-old, scandal-plagued attorney general who won Trump's endorsement last week.

Paxton will face Democratic state Representative James Talarico in a high-profile race that could help decide control of the Senate and may become one of the most expensive in U.S. history.

The 37-year-old Democrat is a Presbyterian seminarian and leading fundraiser whose campaign has appealed to independent and moderate voters. Paxton's supporters quickly attacked his past comments about a nonbinary God and six biological sexes, with Paxton and the Republican National Committee chairman calling him "Tala-freak-o."

Senate Republicans' campaign arm warned in an internal memo last year that a Paxton nomination "would hand Democrats an opening to flip Texas and cause Republicans to divert hundreds of millions of dollars that would otherwise be spent winning key battlegrounds."

Cornyn told supporters he will back the Republican ticket in November.

"I've said throughout this race that I trust the voters of Texas, and they made their decision, and I must respect it," he said in his concession speech.

Republicans hold a 53-47 majority in the Senate over Democrats, who would need to net four seats in November's election to take control of the chamber. Democrats are on defense in two states Trump won in 2024 - Georgia and Michigan - but could win the chamber by holding those two seats and flipping North Carolina, Maine, Ohio and Alaska.

A competitive race in Texas, where no Democrat has won statewide since 1994, would expand the party's path to a majority and potentially force Republicans to redirect investments from more competitive battlegrounds to protect their nominee in a state that Trump carried by nearly 14 percentage points in 2024.

In backing Paxton, Trump chose loyalty over electability as he continues to flex his iron grip over Republican voters. This month, Trump's endorsement of Republican primary challengers ousted incumbents including Louisiana Senator Bill Cassidy and Kentucky Representative Thomas Massie.

Paxton was impeached by the Texas House, indicted for felony fraud, reported to the FBI by his top aides and is being divorced by his wife on biblical grounds, though he has denied any wrongdoing.

In a joint statement, Democratic Senators Chuck Schumer and Kirsten Gillibrand said, "Republicans are facing their nightmare scenario" while Democrats move closer to winning the majority.

Lauren French, a spokesperson for the Democratic Senate Majority PAC, said Paxton's win was a loss for Washington Republicans, who spent nearly $100 million on Cornyn's behalf.

"Even members of his own party call Paxton too corrupt and too damaged for Texas. Now he's the GOP standard-bearer," she said. "Good luck with that."

LOYALTY TRUMPS ELECTABILITY

Talarico starts the general election with a three-month head start after defeating U.S. Representative Jasmine Crockett on March 3.

In a new campaign video released Tuesday night, Talarico said, "The most corrupt politician in America just became the Republican nominee for United States Senate."

Talarico's initial lead in the opinion polls has evaporated, with the most recent survey showing the race in a dead heat against Paxton, with 8% of likely voters undecided.

Cornyn's campaign attacked Paxton's character from the beginning, including calling him "Crooked Ken" and launching a dating game that allows users to swipe on Paxton's alleged mistresses.

Paxton challenged Cornyn to stop the negative ads "for the good of our party."

"We have already changed our TV ad traffic ... to ensure our campaign ends on a positive note (so) that we can focus on beating the leftist lunatic in the fall," Paxton wrote on X last week.

HOUSE RUNOFFS IN SEVERAL DISTRICTS

Voters across the state will also choose their nominees in more than a dozen congressional districts. Both parties' nominees will be chosen in the San Antonio-area 35th district, an open seat Democrats are hoping to flip.

Republicans will choose between state Representative John Lujan and U.S. Air Force veteran Carlos De La Cruz.

Democrats' preferred candidate is Johnny Garcia, a public information officer for Bexar County Sheriff Javier Salazar.

Democrats have accused Republicans of meddling in their primary through a Republican-aligned political committee called Lead Left PAC that has spent nearly $1 million boosting Garcia's opponent, Maureen Galindo, a fringe candidate who has been widely condemned for antisemitic comments.

(Reporting by Nolan D. McCaskill. Editing by Michael Learmonth, Rosalba O'Brien, Cynthia Osterman and Stephen Coates)

U.S. Senator John Cornyn (R-TX) attends a campaign event for re-election in Schertz, Texas, U.S. March 2, 2026. REUTERS/Joel Angel Juarez Joel Angel Juarez Reuters

Copyright Reuters or USA Today Network via Reuters Connect.

This story was originally published May 26, 2026 at 10:18 PM.

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