U.S. 701 is closed at the intersection with Harper Road due to a car crash, according to Horry County Fire Rescue officials.
A two-car, head-on collision is reported.
Assistant Chief Justin Gibbins said four people are injured.
The extent of injuries was not available.
More information will be posted as it becomes available.
Contact AMANDA KELLEY at 626-0381, or follow her at Twitter.com/TSN_akelley.